Real Madrid midfielder Luka Modric could be a doubt for the clash with Paris Saint-Germain on March 6 due to a hamstring injury, Zinedine Zidane has confirmed.
The Croatia international missed training on Tuesday and is set to sit out Wednesday's LaLiga meeting with Leganes at Butarque.
Head coach Zidane hopes the injury is only minor but is uncertain how long Modric will be out of action.
"Modric has a hamstring issue," he told a news conference. "I always have faith in the staff here, the physios and doctors, so he will be back with us quickly. I don't think it is serious."
The injury is the latest to hit the Madrid squad since their 3-1 win over PSG in the first leg of the Champions League last 16 last week.
Toni Kroos has picked up a knee problem and Marcelo limped out of Sunday's 5-3 win over Real Betis with another suspected hamstring issue.
Zidane remains hopeful, though, that all three could return for the meeting at Parc des Princes.
"I am always positive," he said. "I do not like to see today that we have three or four players out injured. I hope they are not out too long, but we will see. I hope it is short.
"It can be that, when there are certain [injury] problems, it's because of an enormous effort. But, at the same time, in order to cope with matches like the one against PSG, we have to repeat those efforts.
"We have to maintain the pressure in every game and to keep doing it for 90 minutes. And doing it every three days is positive.
"When you're winning playing every three days, you're more optimistic. That's what we need now."
|Kerevi recommits to Wallabies, Reds|
|Lyon to ban fan for life after footage of Nazi salute emerges|
|Milan must respect opponents – Gattuso not underestimating Dudelange|
|Copa Libertadores Review: Zarate leads Boca, River draw|
|Mourinho: Dalot can play at Man United for more than 10 years|
|Johnson hoping to erase East Lake demons|
|´No question´ Fitzgerald faces Bears, says Cardinals´ Wilks|
|Rodgers says roughing the passer penalties are ´going the wrong direction´|
|Ravens fined $200,000 for violating communication policy|
|LeBron James set to star in ´Space Jam´ sequel|
|Ronaldo red card ´absurd´, says Pjanic|
|Kovac hails ´special´ Sanches after Bayern goal|
|Marcelino: Tearful Ronaldo said he did nothing wrong|
|Fernandinho takes blame for Man City´s Lyon loss|
|Lovren denies any wrongdoing after perjury charge|
|Plzen boss Vrba slams late mistakes|
|I almost scored as many as Messi - Tagliafico the unlikely hero for Ajax|
|Ronaldo deserves Ballon d´Or not Modric, says Casemiro|
|United fan Rafael - I´ve never lost at City|
|Davis explains abrupt mid-game NFL retirement: ´Football is not for me´|
|Lopes pays tribute to under-fire Lyon coach Genesio|
|Toulon´s Bastareaud handed five-week ban|
|Steelers WR Brown disciplined for missing meeting|
|Arteta refuses to make excuses for Manchester City´s Lyon loss|
|Allegri calls for VAR after Ronaldo´s contentious red card|
|Championship Review: Boro go second, Birmingham still winless|
|Lopetegui: Mariano took his chance|
|Juventus proved their quality after Ronaldo red card - Bonucci|
|Pogba ´class´ impresses Mourinho|
|Man City not Champions League favourites, insists Bernardo Silva|
|Isco calls for Modric to win Ballon d´Or after Champions League win|
|Wawrinka into last eight in St Petersburg|
|Goal hero Pogba is one of the best in the world - Shaw|
|Sane SOS can´t salvage sorry City display|
|Hoffenheim will learn lessons from Shakhtar draw, insists Nagelsmann|
|Valencia 0 Juventus 2: Pjanic hits the spot after Ronaldo sees red|
|Viktoria Plzen 2 CSKA Moscow 2: Krmencik heroics undone by late show|
|Benfica 0 Bayern Munich 2: Sanches returns to haunt his former club|
|Young Boys 0 Manchester United 3: Pogba double inspires Red Devils|
|Manchester City 1 Lyon 2: Cornet and Fekir stun Champions League favourites at home|
|Real Madrid 3 Roma 0: Isco stunner sets up winning start for Champions League holders|
|Ronaldo sent off on Champions League debut for Juve and may miss United reunion|
|Shakhtar Donetsk 2 Hoffenheim 2: Maycon denies Nagelsmann´s side|
|Ajax 3 AEK Athens 0: Tagliafico at the double in opening win|
|Dalot makes debut, Martial starts for Manchester United|
|India avenge ICC Champions Trophy loss with big win over Pakistan|
|Ronaldo makes Champions League debut for Juve|
|Lopetegui picks Navas over Courtois for Champions League clash with Roma|
|Willian very happy under Sarri after Conte row|
|Sarri deals blow to Chelsea kids´ Europa League hopes|
|Mendy out for Manchester City as Aguero makes bench|
|Cech accepts performances key to securing Arsenal stay|
|Monchi rules out Spain return amid Barcelona rumours|
|Durham skittled for 61 and 66 on the same day|
|Kane isn´t a machine – Lamela defends misfiring Spurs star|
|Hazard left out of Chelsea squad for PAOK trip|
|Tiger feels close to ending drought after achieving Tour Championship goal|
|Leno in line for Arsenal chance in Europa League|
|Gazidis leaves Arsenal in good shape, insists Emery|
|Eagles bring back WR Matthews, place Wallace on IR|
|England include Stokes, Hales and uncapped seamer Stone in ODI squad|
|Suwon Bluewings 0 Jeonbuk Motors 3 (aet, 4-2 on penalties): Quarter-final comeback ends in spot-kick|
|Australia captain Paine ready to slog it out with Pakistan|
|Nadal pulls out of China Open & Shanghai Masters with knee injury|
|Ostapenko begins Korea Open defence with victory|
|Joshua v Povetkin: How Olympic super heavyweight champions have fared|
|Liverpool ´made a point´ with PSG victory - Gomez|
|Osaka wows Tokyo crowd on WTA return|
|Excited Povetkin arrives in England for Joshua showdown|
|Kovac patience with Sanches set to reap rewards|